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What is the biggest cause of depression? Causes and Risk Factors of Depression. Depression is one of the most common mental disorders in the United States. Factors that can contribute to depression include genetics, brain chemistry, certain medical conditions, substance use, stress, and poor nutrition.
What does MDD stand for in psychology? Major depressive disorder
Which SSRI is most sedating? The newest SSRIs— citalopram and escitalopram—are the most selective, while the older paroxetine, sertraline, and fluoxetine are much less selec- tive.6 Paroxetine, with more anticholinergic blockade, is generally more sedating than citalopram, but also may al- leviate acute anxiety better.
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