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Patients will be followed for response to subsequent treatments (chemotherapies with or without targeted agents) and survival every 2 months after EOS visit until death.

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IL10 (), which promotes tumour progress after the treatment is ended.

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One such mechanism of action involves the ability to activate innate immune cells through the Toll-like receptor 7 pathway to increase cytokine production.

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Winters U, Daayana S, Lear JT, Tomlinson AE, Elkord E, Stern PL, Kitchener HC (2008) Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia.

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