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Is metformin safe for the liver? CONCLUSION: Metformin does not appear to cause or exacerbate liver injury and, indeed, is often beneficial in patients with nonalcoholic fatty liver disease. Nonalcoholic fatty liver frequently presents with transaminase elevations but should not be considered a contraindication to metformin use.
When should you take metformin morning or night? Metformin alone: At first, 500 milligrams (mg) two times a day taken with the morning and evening meals, or 850 mg a day taken with the morning meal. Your doctor may increase your dose if needed until your blood sugar is controlled.
What metformin does to your body? Insulin is a hormone your body produces to move sugar out of your blood and into cells. By doing this, insulin helps your cells get the energy they need so they can do their jobs. This is known as insulin resistance and can lead to diabetes. As an insulin sensitizer, metformin helps decrease insulin resistance.
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